Fish-derived phosphatidylserines are defined as PS that contains a long chain of polyunsaturated fatt acids (LC-PUFA) of Omega-3. This makes them different from plant-derived of phosphatidylserines which does not contain Omega-3. Vegetable or soy originated type of phosphatidylserines do not contain EPA or DHA is described as fatty acids of Omega-3 (2).

MDHA, the main structural and functional component of the central nervous system, accounts for the majority of the total fatty acid content of membrane phospholipids of the adult human brain. DHA and eicosapentaenoic acid (EPA) play an important role in brain function; both are orthomomolecules whose functional regions are only cell membranes, where they are integrated structurally and functionally through phospholipid molecules. In other words, the connection between EPA, DHA and PS is very important in the nervous system (3).